Relationship between rs854560 PON1 Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease

Table 2

PON1 rs854560 polymorphism genotype and allele frequencies in patient (CAD) and blood donor (BD) groups.

Genotype/allele	CAD; (%)	BD; (%)	Model of inheritance	OR (95% CI)
AA	96 (41.38)	94 (42.53)	Dominant versus AT + TT	0.95 (0.66–1.38)	NS
AT	103 (44.40)	109 (49.32)	Additive versus AA	0.93 (0.63–1.37)	NS
TT	33 (14.22)	18 (8.14)	Additive versus AA	1.80 (0.95–3.41)	NS
			versus AA + AT	1.87 (1.02–3.43)	0.04
AA + AT	199 (85.78)	203 (91.86)	Recessive versus TT	0.53 (0.29–0.98)	0.04
A	295 (63.58)	297 (67.20)	—	0.85 (0.65–1.12)	NS
T	169 (36.42)	145 (32.80)	—	1.17 (0.89–1.54)	NS

NS: not statistically significant; OR: odds ratio.