Relationship between rs854560 PON1 Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease

Table 5

PON1 rs854560 polymorphism genotype and allele frequencies in smoker and nonsmoker groups.

Genotype/allele	Smokers; (%)	Nonsmokers; (%)	Model of inheritance	OR (95% CI)
AA	80 (39.80)	108 (43.72)	Dominant versus AT + TT	0.85 (0.58–1.24)	NS
AT	98 (48.76)	111 (44.94)	Additive versus AA	1.19 (0.80–1.77)	NS
TT	23 (11.44)	28 (11.34)	Additive versus AA	1.11 (0.59–2.07)	NS
			versus AA + AT	1.01 (0.56–1.82)	NS
AA + AT	178 (88.56)	219 (88.66)	Recessive versus TT	0.99 (0.55–1.78)	NS
A	258 (64.18)	327 (66.19)	—	0.92 (0.69–1.21)	NS
T	144 (35.82)	167 (33.81)	—	1.09 (0.83–1.44)	NS

NS: not statistically significant; OR: odds ratio.