FRAX® Fracture Risks Are Associated with Coronary Artery Calcification Score
Table 2
Simple linear regression analysis of coronary artery calcification.
R2
Coefficient
95% CI
value
Std β (r)
Age (years)
0.045
6.27
−0.23–12.76
0.058
0.21
Sex (, )
0.004
35.97
−99.38–171.33
0.598
0.06
Height (cm)
0.005
−2.52
−10.52–5.48
0.532
−0.07
Weight (kg)
0.001
0.64
−4.71–6.00
0.812
−0.03
BMI (kg/m2)
0.008
8.35
−11.87–28.56
0.414
0.09
Smoking
0.002
−45.09
−294.91–204.73
0.720
−0.04
Drinking
0.007
−110.98
−412.17–190.21
0.465
−0.08
Hypertension
0.340
402.36
276.82–527.90
<0.001
0.58
Diabetes mellitus
0.011
99.57
−107.59–306.73
0.342
0.11
Hyperlipidemia
0.175
508.01
260.85–755.17
<0.001
0.42
Secondary osteoporosis
0.018
104.56
−67.03–276.15
0.229
0.14
TCH (mg/dL)
0.019
1.24
−0.75–3.24
0.219
0.14
LDL (mg/dL)
0.013
−1.20
−3.58–1.18
0.320
−0.11
HDL (mg/dL)
<0.001
0.01
−4.40–4.41
0.998
<0.001
Triglycerides (mg/dL)
0.136
1.14
0.50–1.78
0.001
0.37
Glucose (mg/dL)
<0.001
0.16
−3.01–3.33
0.921
0.01
SBP (mmHg)
0.049
2.83
0.02–5.63
0.048
0.22
DBP (mmHg)
0.023
2.92
−1.32–7.16
0.175
0.15
Lumbar spine BMD (g/cm2)
<0.001
2.21
−470.38–474.80
0.993
0.001
Lumbar spine T-score
0.002
−10.21
−64.60–44.18
0.710
−0.04
Right neck BMD (g/cm2)
0.044
−524.47
−1072.08–23.13
0.060
−0.21
Right neck T-score
0.060
−75.63
−142.53–8.74
0.027
−0.25
Right total BMD (g/cm2)
0.002
−102.99
−569.25–363.27
0.661
−0.05
Right total T-score
0.032
−56.90
−126.44–12.64
0.107
−0.18
Left neck BMD (g/cm2)
0.035
−451.74
−980.29–76.81
0.093
−0.19
Left neck T-score
0.046
−63.47
−128.25–1.31
0.055
−0.21
Left total BMD (g/cm2)
0.020
−303.22
−774.01–167.57
0.204
−0.14
Left total T-score
0.088
−96.33
−165.84–26.81
0.007
−0.30
Right MOF (FRAX) (%)
0.103
32.96
11.20–54.71
0.003
0.32
Right HF (FRAX) (%)
0.096
56.27
17.56–94.97
0.005
0.31
Left MOF (FRAX) (%)
0.066
24.34
3.85–44.84
0.021
0.26
Left HF (FRAX) (%)
0.055
39.59
2.74–76.44
0.036
0.23
M: male; F: female; BMI: body mass index; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMD: bone mineral density; MOF: 10-year probability of a major osteoporotic fracture; HF: 10-year probability of a hip fracture; FRAX: fracture risk assessment tool; TBS: trabecular bone score; CAC score: coronary artery calcification score.
