Research Article
Association between Recipient IL-15 Genetic Variant and the Prognosis of HBV-Related Hepatocellular Carcinoma after Liver Transplantation
Table 5
Univariate analysis of prognostic factors associated with DFS and OS.
| Prognostic factors | DFS (months) | | OS (months) | | Odds ratio (95% CI) | value | Odds ratio (95% CI) | value |
| Histologic grade | | | | | (0 = differentiated, 1 = undifferentiated) | 2.093 (1.119–3.915) | 0.021 | 2.194 (1.162–4.139) | 0.015 | Tumor size (0: <5 cm, 1: ≥5 cm) | 3.238 (1.818–5.768) | <0.001 | 3.253 (1.791–5.910) | <0.001 | Tumor thrombus (0 = no, 1 = yes) | 3.893 (2.101–7.015) | <0.001 | 3.791 (2.035–7.060) | <0.001 | Tumor stage (0 = stages I-II, 1 = stage III) | 3.276 (1.818–5.904) | <0.001 | 3.124 (1.695–5.756) | <0.001 | UCSF criteria (0 = no, 1 = yes) | 2.769 (1.556–4.927) | 0.001 | 2.813 (1.552–5.097) | 0.001 | Donor IL-15 rs10519613 genotype | | | | | (0 = CC, 1 = CA/AA) | 2.267 (1.096–4.690) | 0.027 | 1.778 (0.878–3.601) | 0.110 | Recipient IL-15 rs10519613 genotype | | | | | (0 = CC, 1 = CA/AA) | 3.000 (1.447–6.219) | 0.003 | 4.005 (1.776–9.030) | 0.001 |
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DFS: disease-free survival; OS: overall survival; CI: confidence interval.
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