Research Article

Phosphorylation of Histone H2A.X in Peripheral Blood Mononuclear Cells May Be a Useful Marker for Monitoring Cardiometabolic Risk in Nondiabetic Individuals

Figure 3

Relationships between phosphorylated H2A.X (percentage, MFI) and oxidative stress and inflammation and liver function markers. r: correlation coefficient, tested by partial correlation analysis adjusted for age, sex, cigarette smoking, and alcohol consumption; ϕtested after log-transformed; super healthy (•, : narrow solid line) (MetS risk factor = 0) and MetS risk (o, - - -: narrow open line) (MetS risk factor ≥ 1) groups and total subjects (: bold solid line). ALT: alanine aminotransferase; hs-CRP: high-sensitivity C-reactive protein; MFI: mean fluorescence intensity; TNF-α: tumor necrosis factor-alpha.