Disease Markers / 2017 / Article / Tab 2

Research Article

Diagnostic Value of the Methylation of Multiple Gene Promoters in Serum in Hepatitis B Virus-Related Hepatocellular Carcinoma

Table 2

The positive rates of methylation for promoters of 6 genes in serum [n (%)].

GeneHCC patients ()LC patients ()CHB patients ()Healthy controls ()χ2aaχ2bb

RASSF1A51 (52.04)10 (13.33)4 (4.44)3 (3.75)26.2150.00049.0780.000
APC36 (36.73)4 (5.33)2 (2.22)0 (0)21.8340.00032.5430.000
BVES29 (29.59)3 (4.00)1 (1.11)0 (0)16.7990.00026.2920.000
TIMP311 (11.22)2 (2.67)0 (0)0 (0)4.4770.03410.7300.001
GSTP117 (17.35)2 (2.67)0 (0)0 (0)9.3650.00217.1640.000
HOXA920 (20.41)4 (5.33)3 (3.33)0 (0)8.0810.00410.8630.001

HCC: hepatocellular carcinoma; LC: liver cirrhosis; CHB: chronic hepatitis B. aHCC patients versus LC patients, . bHCC patients versus CHB patients, .

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