Disease Markers / 2017 / Article / Tab 3

Research Article

Diagnostic Value of the Methylation of Multiple Gene Promoters in Serum in Hepatitis B Virus-Related Hepatocellular Carcinoma

Table 3

Powers of the methylation statuses of multiple genes and the AFP assay for distinguishing HCC from CHB.

IndicatorSensitivity (%)Specificity (%)AUC

RASSF1A52.091.50.718
APC36.796.40.650
BVES29.697.60.636
TIMP311.298.80.356
GSTP117.498.70.486
HOXA920.495.80.521
AFP (≥20 ng/l)48.073.90.609

HCC: hepatocellular carcinoma; CHB: chronic hepatitis B; AUC: area under the curve.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.