Research Article
Association between Cullin-3 Single-Nucleotide Polymorphism rs17479770 and Essential Hypertension in the Male Chinese Han Population
Table 4
Haplotype frequency distributions of the 2 SNPs of CUL3 in the EH and normotensive groups.
| CUL3 | Haplotype | EH group ratios | Normotensive group ratios | χ2 | value | OR (95% CI) |
| Full data set | CC | 229 : 259 | 207 : 261 | 0.700 | 0.436 | 1.115 (0.864–1.438) | TC | 158 : 259 | 192 : 261 | 1.824 | 0.189 | 0.829 (0.632–1.088) | TT | 131 : 259 | 123 : 261 | 0.213 | 0.647 | 1.073 (0.795–1.449) | Male | CC | 121 : 130 | 102 : 133 | 1.128 | 0.317 | 1.214 (0.849–1.735) | TC | 80 : 130 | 102 : 133 | 1.293 | 0.288 | 0.802 (0.549–1.173) | TT | 59 : 130 | 62 : 133 | 0.015 | 0.913 | 0.974 (0.633–1.498) | Female | CC | 108 : 129 | 105 : 128 | 0.012 | 0.926 | 1.021 (0.710–1.468) | TC | 78 : 129 | 90 : 128 | 0.577 | 0.488 | 0.860 (0.583–1.270) | TT | 72 : 129 | 61 : 128 | 0.545 | 0.521 | 1.171 (0.770–1.782) |
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