Research Article
Soluble Urokinase Plasminogen Activator Receptor and the Risk of Coronary Artery Disease in Young Chinese Patients
Table 1
Demographic and clinical characteristics of CAD patients and controls.
| | CAD group () | Control group () | value |
| | Age (years) | 48.3 ± 9.3 | 49.8 ± 10.4 | 0.14 | | Men (n (%)) | 142 (72.4%) | 92 (48.9%) | <0.0001 | | CAD family history (n (%)) | 15 (7.7%) | 11 (5.9%) | 0.55 | | Current smokers (n (%)) | 76 (38.8%) | 31 (16.5%) | <0.0001 | | Hypertension (n (%)) | 49 (25.0%) | 35 (18.6%) | 0.14 | | Systolic blood pressure (mmHg) | 124.1 ± 12.5 | 123.0 ± 12.8 | 0.39 | | Diastolic blood pressure (mmHg) | 73.2 ± 9.1 | 71.6 ± 8.8 | 0.08 | | Diabetes mellitus (n (%)) | 23 (11.7%) | 17 (9.0%) | 0.41 | | Fasting blood glucose (mg/dl) | 90.3 ± 17.8 | 92.3 ± 16.7 | 0.26 | | Dyslipidemia (n (%)) | 63 (32.1%) | 41 (21.8%) | 0.03 | | TC (mg/dl) | 189.0 ± 38.1 | 184.7 ± 39.5 | 0.28 | | LDL-C (mg/dl) | 129.3 ± 27.9 | 125.1 ± 26.0 | 0.13 | | HDL-C (mg/dl) | 41.5 ± 13.8 | 43.3 ± 13.5 | 0.14 | | TG (mg/dl) | 157.6 ± 29.4 | 146.5 ± 28.2 | 0.0002 | | Overweight/obesity (n (%)) | 61 (31.1%) | 40 (21.3%) | 0.04 | | Body mass index (kg/m2) | 24.8 ± 5.3 | 23.7 ± 4.6 | 0.03 | | eGFR (mL/min/1.73 m2) | 111.2 ± 35.0 | 115.4 ± 39.8 | 0.27 | | hs-CRP (mg/dl) | 5.36 (1.24–11.65) | 2.28 (0.75–7.21) | <0.0001 | | suPAR (ng/ml) | 5.8 (1.3–11.8) | 2.8 (1.0–6.5) | <0.0001 | | 10-year CAD event risk (%) | 5.8 ± 4.7 | 5.0 ± 4.0 | 0.07 |
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Data are presented as mean (±SD), median (interquartile range), or percentages. CAD: coronary artery disease; eGFR: estimated glomerular filtration rate; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; hs-CRP: high-sensitivity C-reactive protein; suPAR: soluble urokinase plasminogen activator receptor.
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