Circulating Tumor Cells Were Associated with the Number of T Lymphocyte Subsets and NK Cells in Peripheral Blood in Advanced Non-Small-Cell Lung Cancer

Table 1

Relationship between the presence of circulating tumor cells (CTCs) and the clinical features of non-small-cell lung cancer.

Clinical features	Number of cases	CTC-positive (%)	CTC-negative (%)	χ2	values
Age
≤60 years old	23	15 (65.2)	8 (34.8)	3.186	0.18
>60 years	60	26 (43.3)	34 (56.7)
Gender
Male	48	24 (50.0)	24 (50.0)	0.017	0.90
Female	35	17 (48.6)	18 (51.4)
Smoking
Yes	36	16 (61.5)	20 (38.5)	0.474	0.49
No	47	25 (53.2)	22 (46.8)
Histological features
Adenocarcinoma	35	17 (48.6)	18 (51.4)	0.184	0.91
Squamous cell carcinoma	41	20 (48.8)	21 (51.2)
Others	7	4 (57.1)	3 (42.9)
Tumor grade
High differentiation	17	5 (29.4)	12 (70.6)	11.183	0.04
Moderate differentiation	36	14 (38.9)	22 (61.1)
Poor differentiation	30	22 (73.3)	8 (26.7)
Pathological stage
IIIA	14	2 (14.3)	12 (85.7)	18.129	0.00
IIIB	17	4 (23.5)	13 (76.5)
IV	52	35 (49.4)	17 (50.6)