Circulating Tumor Cells Were Associated with the Number of T Lymphocyte Subsets and NK Cells in Peripheral Blood in Advanced Non-Small-Cell Lung Cancer
Table 2
Association between NSCLC and different subpopulations of T cells (mean ± SD).
Variables (%)
Control
Stage IIIa
Stage IIIb
Stage IV
F value
value
CD3+
71.7 ± 2.5
69.8 ± 1.6∗
69.7 ± 1.8
65.7 ± 2.7†§
46.7
0.00
CD4+
39.4 ± 0.9
37.0 ± 1.2
36.9 ± 0.9†
31.7 ± 3.5§
74.4
0.00
CD8+
29.2 ± 0.7
29.3 ± 0.9
29.6 ± .9
29.5 ± 1.1
0.79
0.61
CD4+/CD8+
1.4 ± 0.1
1.3 ± 0.1
1.3 ± 0.1
1.1 ± 0.1†§
106.5
0.00
NK
18.1 ± 1.2
15.8 ± 0.9
15.7 ± 0.8
14.6 ± 1.2†§
70.4
0.00
Treg cell
5.4 ± 0.4
7.4 ± 0.5
8.0 ± 1.0
8.9 ± 1.6
63.2
0.01
, versus control; , versus stage IIIa; , versus stage IIIb.
