Prospective and Descriptive Study on Serum Androstenedione Concentration in Healthy Children from Birth until 18 Years of Age and Its Associated Factors

Table 1

Androstenedione reference intervals for children from birth up to adolescence.

Group	Androstenedione (nmol/L)
Full-term 1 year of age
Nonextracted sera
months	3.8 (1.1–7.5)
months	5.6 (0.5–10.1)
2–4 months	1.4 (1.2–2.6)
4–12 months	0.4 (0.3–1.0)
Extracted sera
≤2 months	3.1 (0.5–7.6)
Girls 1 year
Tanner I
1–5 years	0.3 (0.3–1.0)
5–8 years	1.1 (0.3–2.7)
>8 years	2.7 (1.2–4.7)
Tanner II-III	4.0 (1.8–10.1)
Tanner IV-V	6.2 (3.1–10.9)
Boys ≥ 1 year
Tanner I
1–5 years	0.3 (0.3–0.5)
5–9 years	1.3 (0.3–2.8)
>9 years	1.2 (0.3–4.9)
Tanner II-III	3.5 (2.3–6.7)
Tanner IV-V	5.6 (3.0–9.5)

Data are expressed as the median and 3rd–97th centile range.