Disease Markers / 2017 / Article / Tab 1

Research Article

Prospective and Descriptive Study on Serum Androstenedione Concentration in Healthy Children from Birth until 18 Years of Age and Its Associated Factors

Table 1

Androstenedione reference intervals for children from birth up to adolescence.

GroupAndrostenedione (nmol/L)

Full-term 1 year of age
Nonextracted sera
months3.8 (1.1–7.5)
months5.6 (0.5–10.1)
 2–4 months1.4 (1.2–2.6)
 4–12 months0.4 (0.3–1.0)
Extracted sera
 ≤2 months3.1 (0.5–7.6)

Girls 1 year
Tanner I
 1–5 years0.3 (0.3–1.0)
 5–8 years1.1 (0.3–2.7)
 >8 years2.7 (1.2–4.7)
Tanner II-III4.0 (1.8–10.1)
Tanner IV-V6.2 (3.1–10.9)

Boys ≥ 1 year
Tanner I
 1–5 years0.3 (0.3–0.5)
 5–9 years1.3 (0.3–2.8)
 >9 years1.2 (0.3–4.9)
Tanner II-III3.5 (2.3–6.7)
Tanner IV-V5.6 (3.0–9.5)

Data are expressed as the median and 3rd–97th centile range.