PROM and Labour Effects on Urinary Metabolome: A Pilot Study

Table 2

Statistically significant (FDR < 0.05) metabolites from the t-test of the classes Ph2 versus Ph3.

Metabolite	Chemical class	value	FDR	Ph2 versus Ph3
Gulonic acid	Ox			Down
Erythronic acid	Ox			Down
2,3,4,5-Tetrahydroxypentanoic acid 1.4-lactone	Ox	3,53E-03		Down
cis-Aconitic acid	Misc	4,44E-02		Down
Glucaric acid	Ox			Down
Pyroglutamic acid	Misc			Down
Ribitol	SR			Down
Arabitol	SR			Down
Fucose	Carb			Down
Unknown C	Misc		0.00010306	Down
Tyrosine	AA		0.0001065	Down
Erythritol	SR		0.00011968	Down
Pseudouridine	Misc		0.00015105	Down
3,4-Dihydroxybutyric acid	Misc		0.00023071	Down
Monosaccharide 1886	Carb		0.00026311	Down
Xylobiose	Carb		0.00027903	Down
Gluconic acid	Ox		0.00029457	Down
Histidine	AA		0.00029457	Down
4-Deoxythreonic acid	Ox		0.00029457	Down
3-Hydroxybutyric acid	Misc		0.00034512	Down
Phenylalanine	AA	0.00010095	0.00034512	Down
Monosaccharide E	Carb	0.0001043	0.00034512	Down
3,4,5-Trihydroxypentanoic acid	Ox	0.00010624	0.00034512	Down
Sedoheptulose	Carb	0.00010757	0.00034512	Down
Quinolinic acid	Misc	0.00012733	0.00039216	Down
Xylitol	SR	0.00017953	0.00053168	Down
Phosphate	Misc	0.00020953	0.00059755	Up
Lysine	AA	0.000373	0.0010074	Down
Succinic acid	Misc	0.00037941	0.0010074	Down
Ribose	Carb	0.00049401	0.001268	Down
Threonine	AA	0.00055591	0.0013069	Down
Cystine	AA	0.00056022	0.0013069	Down
2-Amino-6-hydroxy-7-methyl-7H-purine	Misc	0.00056835	0.0013069	Down
Serine	AA	0.00057708	0.0013069	Down
N-Acetylglucosamine	SR	0.00074989	0.0016498	Down
Citric acid	Misc	0.0009237	0.0019757	Down
Ribonic acid	Ox	0.0013077	0.0027213	Down
Glutamine	AA	0.0014072	0.0028515	Down
Lactose	Carb	0.0020445	0.0040365	Up
Glucose	Carb	0.0024816	0.004777	Down
Hydroxyproline dipeptide	AA	0.0028275	0.0053102	Down
Glycine, N-4-hydroxybenzoyl	Misc	0.0038577	0.0070724	Down
2-Ketogluconic acid	Ox	0.0045002	0.0080016	Down
2,4-Dihydroxybutyric acid	Misc	0.0045723	0.0080016	Down
Threonic acid	Ox	0.0047704	0.0081627	Down
4-Hydroxyphenylacetic acid	Misc	0.0051136	0.0085598	Down
Alanine	AA	0.0052474	0.0085968	Down
2-O-Glycerol-galactopyranoside	SR	0.0071983	0.011547	Down
Threitol	SR	0.0091347	0.014354	Down
Glycine, N-4-hydroxybenzoyl derivative	Misc	0.010305	0.015869	Down
Creatinine	Misc	0.012953	0.019557	Down
Uric acid	Misc	0.014046	0.020799	Up
3-Methylhistidine	AA	0.014579	0.02117	Down
Glyceromannoheptonic acid	Ox	0.014847	0.02117	Down
Hippuric acid	Misc	0.015776	0.022086	Down
Inositol	SR	0.016169	0.022232	Down
Arabinose	Carb	0.017089	0.023086	Down
4-Deoxyerythronic acid	Ox	0.017767	0.023587	Down
Ethanolamine	Misc	0.024206	0.031591	Down
Mannitol	SR	0.026258	0.033697	Down