Identifying the Best Marker Combination in CEA, CA125, CY211, NSE, and SCC for Lung Cancer Screening by Combining ROC Curve and Logistic Regression Analyses: Is It Feasible?

Table 1

Concentrations of serum markers in patients with lung cancer and pneumonia and healthy subjects.

	CEA (ng/mL)	CY211 (ng/mL)	NSE (ng/mL)	CA125 (U/mL)	SCC (ng/mL)
Lung cancer	3.44 (1.88, 12.20)^#	3.20 (2.08, 6.24)^#	13.76 (11.38, 18.33)^#	24.55 (12.09, 63.89)^#	0.70 (0.44, 1.24)
Pneumonia	2.18 (1.39, 3.35)^&	2.21 (1.57, 3.32)^&	12.08 (9.78, 14.64)^&	15.13 (10.16, 31.16)^&	0.80 (0.50, 1.40)^&
Healthy	1.27 (0.57, 2.06)	2.10 (1.61, 2.70)	12.37 (10.86, 14.27)	11.60 (8.44, 15.88)	0.68 (0.40, 0.99)

Compared with healthy subjects, , 13.97, 7.74, 16.56, and 4.22; . , 2.94, 2.23, 10.18, and 7.05; . ^#Compared with pneumonia patients, , 10.03, 8.32, and 7.29; .