Impact of Proteinase 3 versus Myeloperoxidase Positivity on Risk of End-Stage Renal Disease in ANCA-Associated Glomerulonephritis Stratified by Histological Classification: A Population-Based Cohort Study

Table 1

Baseline characteristics in the total cohort and stratified for MPO- and PR3-ANCA.

Characteristic	All,	MPO-ANCA,	PR3-ANCA,	value
Males (%)	187 (52)	68 (41)	119 (62)	<0.001
Mean age (SD)	60 (17)	64 (15)	58 (18)	0.001
eGFR (SD)	34 (30)	31 (28)	36 (32)	0.07
Serum albumin (SD)	32 (7)	32 (7)	31 (7)	0.04
Systolic blood pressure (SD)	142 (21)	144 (21)	141 (21)	0.08
Diastolic blood pressure (SD)	80 (11)	82 (11)	79 (11)	0.05
Proteinuria (SD)	1.8 (2.0)	1.9 (2.0)	1.7 (2.0)	0.25
Percentage normal glomeruli (SD)	36 (29)	33 (28)	38 (30)	0.07
Focal histology (%)	127 (35)	53 (32)	74 (38)	0.21
Mixed histology (%)	90 (25)	40 (25)	50 (26)	0.82
Crescentic histology (%)	106 (30)	45 (27)	61 (32)	0.32
Sclerotic histology (%)	35 (10)	27 (16)	8 (4)	<0.001