Research Article

Identification of Common Genes Refers to Colorectal Carcinogenesis with Paired Cancer and Noncancer Samples

Table 1

Go analysis of DEGs between paired tumor and nontumor sample.

ExpressionCategoryTerm/gene functionCount% value

UpregulatedGOTERM_BP_DIRECTGO:0051301~cell division228.251.48E − 11
GOTERM_BP_DIRECTGO:0007067~mitotic nuclear division197.132.06E − 11
GOTERM_BP_DIRECTGO:0000281~mitotic cytokinesis72.632.51E −07
GOTERM_BP_DIRECTGO:0030574~collagen catabolic process83.002.26E − 06
GOTERM_BP_DIRECTGO:0006260GO:0000082~G1/S transition of mitotic cell cycle93.385.34E − 06
GOTERM_CC_DIRECTGO:0005654~nucleoplasm5119.134.95E − 07
GOTERM_CC_DIRECTGO:0005876~spindle microtubule72.632.49E − 06
GOTERM_CC_DIRECTGO:0000922~spindle pole93.386.09E − 06
GOTERM_CC_DIRECTGO:0005819~spindle83.001.08E − 04
GOTERM_CC_DIRECTGO:0005578~proteinaceous extracellular matrix114.131.53E − 04
GOTERM_MF_DIRECTGO:0005109~frizzled binding51.883.70E − 04
GOTERM_MF_DIRECTGO:0005515~protein binding10639.754.65E − 04
GOTERM_MF_DIRECTGO:0008017~microtubule binding93.388.73E − 04
GOTERM_MF_DIRECTGO:0019901~protein kinase binding124.509.80E − 04
GOTERM_MF_DIRECTGO:0008009~chemokine activity51.880.0012

DownregulatedGOTERM_BP_DIRECTGO:0015701~bicarbonate transport82.132.88E − 06
GOTERM_BP_DIRECTGO:0045926~negative regulation of growth61.605.88E − 06
GOTERM_BP_DIRECTGO:0071294~cellular response to zinc ion61.605.88E − 06
GOTERM_BP_DIRECTGO:0006730~one-carbon metabolic process61.606.33E − 05
GOTERM_BP_DIRECTGO:0007586~digestion71.872.88E − 04
GOTERM_CC_DIRECTGO:0070062~extracellular exosome7520.004.45E − 08
GOTERM_CC_DIRECTGO:0005615~extracellular space4211.202.88E − 06
GOTERM_CC_DIRECTGO:0031526~brush border membrane71.878.19E − 05
GOTERM_CC_DIRECTGO:0048471~perinuclear region of cytoplasm195.070.0035
GOTERM_CC_DIRECTGO:0016021~integral component of membrane9324.810.0067
GOTERM_MF_DIRECTGO:0004089~carbonate dehydratase activity51.333.51E − 05
GOTERM_MF_DIRECTGO:0005254~chloride channel activity71.871.11E − 04
GOTERM_MF_DIRECTGO:0016491~oxidoreductase activity102.670.0022
GOTERM_MF_DIRECTGO:0008201~heparin binding82.130.0080
GOTERM_MF_DIRECTGO:0005179~hormone activity61.600.0108