Soluble HLA-I and HLA-II Molecules Are Potential Prognostic Markers of Progression of Systemic and Local Inflammation in Patients with COPD

Figure 1

The concentration of sHLA-I molecules in blood serum and exhaled breath condensate in COPD patients during the exacerbation and in the stable period. Data are presented as mean ± SD. Control: healthy nonsmoking volunteers, II: moderate COPD, III: severe COPD, ex: exacerbation, and st: stable phase. versus healthy nonsmokers, ^# versus patients with moderate COPD during the exacerbation, ^∨ versus patients with moderate COPD in the stable phase, and ^{^} versus patients with severe COPD during the exacerbation.