A Noninvasive Score to Predict Liver Fibrosis in HBeAg-Positive Hepatitis B Patients with Normal or Minimally Elevated Alanine Aminotransferase Levels

Table 5

Comparison of performance of the score system with HBeAg, LSM, APRI, FIB-4, and GPR for liver fibrosis.

	AUROC (95% CI)	SE
Score system	0.880 (0.827, 0.921)	0.0304
HBeAg	0.822 (0.762, 0.872)	0.0365	2.273	0.023
LSM	0.791 (0.728, 0.845)	0.0443	2.654	0.0079
APRI	0.720 (0.653, 0.780)	0.0461	3.784	0.0002
FIB-4	0.671 (0.601, 0.735)	0.0502	4.247	<0.0001
GPR	0.687 (0.619,0.750)	0.0489	4.190	<0.0001

Compared with the score system. LSM: liver stiffness measurement; APRI: aspartate aminotransferase-to-platelet ratio index; FIB-4: fibrosis index based on 4 factors; GPR: gamma-glutamyltranspeptidase-to-platelet ratio.