TGF-β Polymorphisms Are a Risk Factor for Chagas Disease

Table 4

Heterogeneity analysis of the relative risk of the TGFB1 +10 T/C polymorphism among noninfected subjects and patients with Chagas disease from Colombian, Peruvian, and Brazilian populations using the method suggested by Woolf [30].

(a)

Population	Chagas disease		Noninfected		Total	OR	95% CI (OR)
	C	T	C	T
Peru	94	42	95	69	300	1.6182	1.0073	2.5994
Colombia	376	174	233	161	944	1.4932	1.1405	1.9526
Brazil	183	121	45	51	400	1.7140	1.0813	2.7025
Total	653	337	373	281	1644	1.4598	1.1908	1.7865

(b)

Heterogeneity test
Source	x^2	df
Significance	13.3043	1	0.0003
Heterogeneity	4.397	2	0.1086
Total	17.7440	3	0.0005