Clinical Significance of Hemostatic Parameters in the Prediction for Type 2 Diabetes Mellitus and Diabetic Nephropathy

Table 5

Predicting power of the independent risk factors for T2DM and DN.

Complications	Variables	AUC		95% CI		Cutoff value	Sensitivity (%)	Specificity (%)
				Lower	Upper
Noncomplications	APTT	0.592	0.018	0.517	0.667	24.3 s	60	89
	PLT	0.647	0.000	0.577	0.718	176 × 10^9/L	65	86
	aPTT and PLT	0.694	0.00	0.634	0.755	ND	70	82
Nephropathy	FIB	0.874	0.000	0.830	0.921	3.15 g/L	85	76
	PLT	0.564	0.133	0.477	0.602	205 × 10^9/L	60	89
	FIB and PLT	0.883	0.000	0.840	0.933	ND	90	72

AUC: area under curve; T2DM: type 2 diabetes mellitus; DN: diabetic nephropathy; CI: confidence interval; aPTT: activated partial thromboplastin time; PLT: platelet count; FIB: fibrinogen; ND: no data; CI: confidence interval.