Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer

<div>The knockdown of TUG1 represses the growth, invasion, and migration of BxPC-3 and PANC-1 cells. (a) qRT-PCR was used to determine the expression of lncRNA TUG1 in BxPC-3 (left) and PANC-1 (right) cells after Lv-TUG1 shRNA transfection. (b) CCK-8 was used to measure the proliferation of BxPC-3 (left) and PANC-1 (right) cells after Lv-TUG1 shRNA treatment. (c) Transwell assay was used to measure the invasive ability of BxPC-3 (left) and PANC-1 (right) cells after Lv-TUG1 shRNA treatment. (d) Wound healing assay was used to measure the migratory ability of PANC-1 cells after Lv-TUG1 shRNA treatment. Similar results were also obtained in BxPC-3 cells (data not shown). 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Disease Markers

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Figure 2

Figure 2: Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer 