Rab27b Is a Potential Indicator for Lymph Node Metastasis and Unfavorable Prognosis in Lung Adenocarcinoma

Table 2

Univariate and multivariate analyses of prognostic factors for overall survival in 80 LUAD cases.

	Univariate analysis			Multivariate analysis
	HR	value	95% CI	HR	value	95% CI
Rab27b expression
High versus low	2.54	0.002	1.42–4.57	2.31	0.006	1.27–4.22
Gender
Male versus female	1.19	0.497	0.72–1.96
Age
≥60 years versus <60 years	0.94	0.811	0.56–1.57
Tumor diameter
≥3 cm versus <3 cm	1.43	0.190	0.84–2.45
Pathological grade
Grades I–II versus grade III	0.91	0.728	0.52–1.57
Lymph node metastasis
Positive versus negative	2.07	0.007	1.23–3.50	0.74	0.507	0.30–1.81
T status
T1–T2 versus T3–T4	0.70	0.212	0.39–1.23
N status
Positive versus negative	1.87	0.014	1.14–3.08	1.65	0.143	0.84–3.22
M status
Positive versus negative	1.05	0.962	0.14–7.61
TNM stage
Stages I–II versus stages III–IV	0.43	0.001	0.25–0.71	0.45	0.027	0.22–0.91

; HR: hazard ratio; CI: confidence interval; LUAD: lung adenocarcinoma.