Trends in Survival of Patients with Primary Gastric Diffuse Large B-Cell Lymphoma: An Analysis of 7051 Cases in the SEER Database

Table 2

Univariate and multivariate analysis of clinical parameters associated with overall survival in primary gastric DLBCL.

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)		Hazard ratio (95% CI)
Year of diagnosis
1973–2000	Reference		Reference
2001–2014	0.926 (0.868 to 0.988)	0.020	0.892 (0.836 to 0.952)	0.001
Age, years
<60	Reference		Reference
≥60	2.249 (2.076 to 2.437)	<0.001	2.383 (2.196 to 2.585)	<0.001
Race
Black	Reference		Reference
White	0.922 (0.823to 1.032)	0.158	0.796 (0.710 to 0.892)	<0.001
Other	0.725 (0.627to 0.838)	<0.001	0.662 (0.572 to 0.765)	<0.001
Stage
Early stage	Reference		Reference
Advanced stage	1.571 (1.473 to 1.676)	<0.001	1.666 (1.561 to 1.778)	<0.001
Sex
Male	Reference		Reference
Female	1.004 (0.944 to 1.068)	0.894	0.931 (0.875 to 0.991)	0.024