Prognostic Role of MicroRNAs in Human Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis

Table 3

MicroRNA regulation (upregulated and downregulated) reported from the selected studies.

Consistently reported upregulated and downregulated miRNAs in selected studies
Upregulated miRNAs			Downregulated miRNAs
miRNA	Number of studies (reference)	Number of samples	miRNA	Number of studies (reference)	Number of samples
miR-21	8 [16, 18–20, 24–27]	1871	miR-let-7	5 [18, 20, 21, 29, 32]	1445
miR-155	6 [15–17, 20, 28, 29]	2176	miR-30a	4 [14, 25, 26, 31]	380
miR-182	5 [14, 18, 21, 28, 31]	709	miR-126	4 [25, 26, 28, 29]	433
miR-210	4 [14, 28, 29, 31]	605	miR-181a	3 [18, 25, 26]	242
miR-31	4 [14, 25, 26, 31]	480	miR-143	3 [25, 26, 29]	362
miR-191	3 [17, 28, 29]	383	miR-486-5p	2 [14, 31]	226
miR-205	3 [18, 27, 29]	392	miR-375	2 [13, 51]	313
miR-200a	2 [23, 28]	339	miR-148a	2 [22, 33]	426
miR-412	2 [25, 26]	154	miR-34b	2 [14, 20]	845
miR-135b	2 [14, 26]	300	miR-148b	2 [34, 35]	380
miR-34a	2 [20, 25]	699	miR-29c	2 [25, 52]	234
miR-192	2 [29, 30]	342	miR-29a	2 [25, 26]	154