Table of Contents Author Guidelines Submit a Manuscript
Disease Markers
Volume 2018, Article ID 8403937, 8 pages
https://doi.org/10.1155/2018/8403937
Research Article

Serum Cytokine Profiles in Patients with Dengue Fever at the Acute Infection Phase

1First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
2State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
3HKU-Pasteur Research Pole, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong

Correspondence should be addressed to Yingchun Zhou; moc.621@ybabnuhcgniy

Junyuan Huang and Weiwen Liang contributed equally to this work.

Received 1 November 2017; Revised 22 December 2017; Accepted 2 January 2018; Published 30 January 2018

Academic Editor: Hyundoo Hwang

Copyright © 2018 Junyuan Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Bhatt, P. W. Gething, O. J. Brady et al., “The global distribution and burden of dengue,” Nature, vol. 496, no. 7446, pp. 504–507, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. C. Guo, Z. Zhou, Z. Wen et al., “Global epidemiology of dengue outbreaks in 1990–2015: a systematic review and meta-analysis,” Frontiers in Cellular and Infection Microbiology, vol. 7, pp. 7–317, 2017. View at Publisher · View at Google Scholar
  3. M. G. Guzman, M. Alvarez, and S. B. Halstead, “Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection,” Archives of Virology, vol. 158, no. 7, pp. 1445–1459, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. L. Zhao, X. Huang, W. Hong et al., “Slow resolution of inflammation in severe adult dengue patients,” BMC Infectious Diseases, vol. 16, no. 1, article 291, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. Tang, Z. Kou, F. Zhang et al., “Both viremia and cytokine levels associate with the lack of severe disease in secondary dengue 1 infection among adult Chinese patients,” PLoS One, vol. 5, no. 12, article e15631, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. R. A. D. S. Oliveira, M. T. Cordeiro, P. M. M. F. Moura et al., “Serum cytokine/chemokine profiles in patients with dengue fever (DF) and dengue hemorrhagic fever (FHD) by using protein array,” Journal of Clinical Virology, vol. 89, pp. 39–45, 2017. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Pandey, A. Jain, R. K. Garg, R. Kumar, O. P. Agrawal, and P. V. Lakshmana Rao, “Serum levels of IL-8, IFNγ, IL-10, and TGF β and their gene expression levels in severe and non-severe cases of dengue virus infection,” Archives of Virology, vol. 160, no. 6, pp. 1463–1475, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Guo, J. Lin, L. Li et al., “The prevalence and endemic nature of dengue infections in Guangdong, South China: an epidemiological, serological, and etiological study from 2005–2011,” PLoS One, vol. 9, no. 1, article e85596, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. A. A. James, Z.-R. Lun, J.-Y. Wu, and X.-G. Chen, “Dengue fever in mainland China,” The American Journal of Tropical Medicine and Hygiene, vol. 83, no. 3, pp. 664–671, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Lai, Z. Huang, H. Zhou et al., “The changing epidemiology of dengue in China, 1990–2014: a descriptive analysis of 25 years of nationwide surveillance data,” BMC Medicine, vol. 13, no. 1, article 100, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Huang, X. Luo, J. Shao et al., “Epidemiology and characteristics of the dengue outbreak in Guangdong, Southern China, in 2014,” European Journal of Clinical Microbiology & Infectious Diseases, vol. 35, no. 2, pp. 269–277, 2016. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. P. Lin, Y. Luo, Y. Chen et al., “Clinical and epidemiological features of the 2014 large-scale dengue outbreak in Guangzhou city, China,” BMC Infectious Diseases, vol. 16, no. 1, p. 102, 2016. View at Publisher · View at Google Scholar · View at Scopus
  13. World Health Organization and the Special Programme for Research and Training in Tropical Diseases (TDR), Dengue guidelines for diagnosis, treatment, prevention and control: new edition, http://www.who.int/rpc/guidelines/9789241547871/en/.
  14. N. A. Dalrymple and E. R. Mackow, “Endothelial cells elicit immune-enhancing responses to dengue virus infection,” Journal of Virology, vol. 86, no. 12, pp. 6408–6415, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. A. L. Rothman, “Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms,” Nature Reviews Immunology, vol. 11, no. 8, pp. 532–543, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Egesten, M. Eliasson, H. M. Johansson et al., “The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes,” The Journal of Infectious Diseases, vol. 195, no. 5, pp. 684–693, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. S. A. Reid-Yu, B. R. Tuinema, C. N. Small, L. Xing, and B. K. Coombes, “CXCL9 contributes to antimicrobial protection of the gut during Citrobacter rodentium infection independent of chemokine-receptor signaling,” PLoS Pathogens, vol. 11, no. 2, article e1004648, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. W. Huang, K. Hu, S. Luo et al., “Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway,” The Journal of Immunology, vol. 188, no. 12, pp. 6247–6257, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. E. Simon-Lorière, V. Duong, A. Tawfik et al., “Increased adaptive immune responses and proper feedback regulation protect against clinical dengue,” Science Translational Medicine, vol. 9, no. 405, article eaal5088, 2017. View at Publisher · View at Google Scholar
  20. J.-P. Chen, H.-L. Lu, S.-L. Lai et al., “Dengue virus induces expression of CXC chemokine ligand 10/IFN-γ-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate,” The Journal of Immunology, vol. 177, no. 5, pp. 3185–3192, 2006. View at Publisher · View at Google Scholar
  21. K. L. Wong, W. Chen, T. Balakrishnan, Y. X. Toh, K. Fink, and S.-C. Wong, “Susceptibility and response of human blood monocyte subsets to primary dengue virus infection,” PLoS One, vol. 7, no. 5, article e36435, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. P. P. Ip and F. Liao, “Resistance to dengue virus infection in mice is potentiated by CXCL10 and is independent of CXCL10-mediated leukocyte recruitment,” The Journal of Immunology, vol. 184, no. 10, pp. 5705–5714, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. P. Fallahi and G. Elia, “Interferon-γ-induced protein 10 in dengue virus infection,” La Clinica Terapeutica, vol. 167, no. 6, pp. e186–e191, 2016. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Guabiraba, R. E. Marques, A.-G. Besnard et al., “Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice,” PLoS One, vol. 5, no. 12, article e15680, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. I. Kurane, “Dengue hemorrhagic fever with special emphasis on immunopathogenesis,” Comparative Immunology, Microbiology and Infectious Diseases, vol. 30, no. 5-6, pp. 329–340, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. J. E. Cardier, E. Mariño, E. Romano et al., “Proinflammatory factors present in sera from patients with acute dengue infection induce activation and apoptosis of human microvascular endothelial cells: possible role of TNF-α in endothelial cell damage in dengue,” Cytokine, vol. 30, no. 6, pp. 359–365, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. M. M. Mangada and A. L. Rothman, “Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes,” The Journal of Immunology, vol. 175, no. 4, pp. 2676–2683, 2005. View at Publisher · View at Google Scholar
  28. A. Rathakrishnan, S. M. Wang, Y. Hu et al., “Cytokine expression profile of dengue patients at different phases of illness,” PLoS One, vol. 7, no. 12, article e52215, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. S. I. de la Cruz Hernández, H. N. Puerta-Guardo, H. Flores Aguilar et al., “Primary dengue virus infections induce differential cytokine production in Mexican patients,” Memórias do Instituto Oswaldo Cruz, vol. 111, no. 3, pp. 161–167, 2016. View at Publisher · View at Google Scholar · View at Scopus