ABCC4 Variants Modify Susceptibility to Kawasaki Disease in a Southern Chinese Population

Table 3

Stratification analysis of susceptibility in Kawasaki disease patients.

Variables	Combined effect of risk genotypes (patients/controls)		value^a	OR (95% CI)	value	Adjusted OR (95% CI)	value^b
	0–4	5-6
Age, months
<12	163/162	22/15	0.2818	1.46 (0.73–2.91)	0.2854	1.46 (0.73–2.91)	0.2855
12–60	475/516	52/34	0.0253	1.66 (1.06–2.61)	0.0270	1.65 (1.05–2.59)	0.0296
>60	53/44	10/3	0.1155	2.77 (0.72–10.68)	0.1397	3.52 (0.87–14.33)	0.0790
Gender
Male	477/488	47/37	0.2510	1.30 (0.83–2.04)	0.2526	1.31 (0.84–2.06)	0.2378
Female	214/234	37/15	0.0012	2.70 (1.44–5.05)	0.0020	2.69 (1.43–5.03)	0.0021
Coronary artery outcomes
CAA	91/722	12/52	0.0904	1.83 (0.94–3.56)	0.0744	1.84 (0.94–3.60)	0.0748
CAL	170/722	17/52	0.2727	1.39 (0.78–2.46)	0.2609	1.39 (0.78–2.47)	0.2619
NCAL	430/722	55/52	0.0047	1.78 (1.19–2.64)	0.0046	1.77 (1.18–2.63)	0.0053

^aχ² test for genotype distributions between Kawasaki disease patients and controls; ^badjusted for age and gender.