Combined Use of High-Sensitive Cardiac Troponin, Copeptin, and the Modified HEART Score for Rapid Evaluation of Chest Pain Patients

Table 1

Composition of the modified HEART score.

Age	Electrocardiogram	Risk factors	Clinical presentation	Points
≥65 years	ST segment depression/elevation	≥3 risk factors or history of CAD	High suspicion (3/3 criteria)	2
45–64 years	LBBB and LVH	1 or 2 risk factors	Moderate suspicion (2/3 criteria)	1
<45 years	Nonspecific changes	No risk factors	Low suspicion (0–1/3 criteria)	0

CAD: coronary artery disease; LBBB: left bundle branch block; LVH: left ventricular hypertrophy. Considered risk factors: hypertension, diabetes mellitus, and smoking history. History of coronary artery disease included the history of myocardial infarction, cardiac revascularization, or former diagnosis of coronary artery disease. Considered criteria: type of chest pain claimed as pressure, aggravation of chest pain with physical activity, and radiation to arms and/or shoulders.