Comparative Clinical Analysis of Gastroenteropancreatic Neuroendocrine Carcinomas with Liver Metastasis and Primary Hepatic Neuroendocrine Carcinomas

Table 4

Immunohistochemistry results of hepatic neuroendocrine carcinomas.

Markers	Group		values^a
	Primary group	Metastatic group
Syn			0.557
Positive	12	31
Negative	0	3
CgA			1.000
Positive	9	23
Negative	3	10
CD56			0.659
Positive	9	26
Negative	1	8
Glypican-3			0.175
Positive	4	3
Negative	5	15
PCK			0.286
Positive	7	20
Negative	1	0
CK7			0.438
Positive	5	15
Negative	5	7
CK19
Positive	6	18
Negative	3	5	0.654
EMA			1.000
Positive	4	11
Negative	1	3

Syn = synaptophysin, CgA = chromogranin A, PCK = phosphoenolpyruvate carboxykinase, CK7 = cytokeratin 7, TTF–1 = thyroid transcription factor, CK19 = cytokeratin 19, EMA = epithelial membrane antigen. ^aFisher’s exact test.