Association between Serum Copeptin and Stroke in Rural Areas of Northern China: A Matched Case-Control Study
Table 2
Association between the level of serum copeptin and total stroke, ischemic stroke, and hemorrhagic stroke.
Level of serum copeptin
Tertile 1
Tertile 2
Tertile 3
Total stroke ( sets)
Copeptin range (pmol/L)
<7.256
7.256~16.440
>16.440
Number of cases/controls
37/40
28/39
54/40
OR (95% CI)
1.00 (reference)
0.77 (0.39–1.54)
1.45 (0.78–2.69)
OR (95% CI)a
1.00 (reference)
0.70 (0.33–1.49)
1.23 (0.62–2.44)
a
0.052
Ischemic stroke ( sets)
Copeptin range (pmol/L)
<6.478
6.478~13.599
>13.599
Number of cases/controls
17/29
15/30
55/28
OR (95% CI)
1.00 (reference)
0.82 (0.33–2.05)
3.99 (1.66–9.57)
OR (95% CI)b
1.00 (reference)
0.79 (0.28–2.21)
4.01 (1.47–10.96)
b
0.002
Hemorrhagic stroke ( sets)
Copeptin range (pmol/L)
<8.425
8.425~26.019
>26.019
Number of cases/controls
19/10
11/12
2/10
OR (95% CI)
1.00 (reference)
0.44 (0.13–1.43)
0.13 (0.22–0.69)
0.011
aThe OR was adjusted by personal history of hypertension, smoking status, and pickle intake. bThe OR was adjusted by BMI, personal history of hypertension, smoking status, and pickle intake. : value for trend was derived from conditional logistic regression in which serum copeptin levels were used as continuous variables and adjusted by related factors.
