Disease Markers / 2018 / Article / Tab 2

Research Article

Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer

Table 2

Clinicopathologic characteristics of patients according to breast cancer phenotype.

ParameterTotal
()
(%)
Luminal A
()
(%)
Luminal B
()
(%)
HER-2
()
(%)
TNBC
()
(%)
value

Age (years)0.299
 ≤50202 (58.0)94 (58.0)55 (65.5)13 (48.1)40 (53.3)
 >50146 (42.0)68 (42.0)29 (34.5)14 (51.9)35 (46.7)
Histologic grade<0.001
 I/II242 (69.5)147 (90.7)53 (63.1)12 (44.4)30 (40.0)
 III106 (30.5)15 (9.3)31 (36.9)15 (55.6)45 (60.0)
Tumor stage0.068
 T1182 (52.3)96 (59.3)42 (50.0)13 (48.1)31 (41.3)
 T2/T3166 (47.7)66 (40.7)42 (50.0)14 (51.9)44 (58.7)
Nodal metastasis0.676
 Absent208 (59.8)94 (58.0)48 (57.1)17 (63.0)49 (65.3)
 Present140 (40.2)68 (42.0)36 (42.9)10 (37.0)26 (34.7)
Estrogen receptor status<0.001
 Negative107 (30.7)2 (1.2)3 (3.6)27 (100.0)75 (100.0)
 Positive241 (69.3)160 (98.8)81 (96.4)0 (0.0)0 (0.0)
Progesterone receptor status<0.001
 Negative149 (42.8)20 (12.3)27 (32.1)27 (100.0)75 (100.0)
 Positive199 (57.2)142 (87.7)57 (67.9)0 (0.0)0 (0.0)
HER-2 status<0.001
 Negative280 (80.5)162 (100.0)43 (51.2)0 (0.0)75 (100.0)
 Positive68 (19.5)0 (0.0)41 (48.8)27 (100.0)0 (0.0)
Ki-67 LI (%)<0.001
 ≤14213 (61.2)162 (100.0)24 (28.6)13 (48.1)14 (18.7)
 >14135 (38.8)0 (0.0)60 (71.4)14 (51.9)61 (81.3)

TNBC: triple-negative breast cancer.