Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer

Table 4

Univariate analysis of the impact of expression of pentose phosphate pathway-related proteins in breast cancers on disease-free survival and overall survival by the log-rank test.

Parameter	Number of patients/recurrence/death	Disease-free survival		Overall survival
		Mean survival (95% CI) months	value	Mean survival (95% CI) months	value
G6PDH			0.752		0.377
Negative	297/28/28	126 (122–131)		129 (125–133)
Positive	51/4/7	122 (114–130)		120 (109–131)
6PGL			0.239		0.569
Negative	261/20/24	129 (124–133)		129 (124–133)
Positive	87/12/11	116 (109–124)		125 (117–133)
6PGDH			n/a		n/a
Negative	343/32/35	n/a		n/a
Positive	5/0/0	n/a		n/a
NRF2			n/a		n/a
Negative	311/32/35	n/a		n/a
Positive	37/0/0	n/a		n/a