Research Article

Diagnosis and Prognosis of Sepsis Based on Use of Cytokines, Chemokines, and Growth Factors

Table 1

Clinical characteristics and baseline demographics of the 80 sepsis patientsa.

Characteristics

Demographics
Female/male (, %)36/44(45/55%)
Age (years, range)74.5(38-87)
Age >65/<6558/22(72.5/27.5%)
Clinical parameters
APACHE II score26.2(3-38.9)
SOFA score4(2-13)
Laboratory data
PaO2/FiO2140(45-920)
Lactate (mmol/L)2.1(0.3-14.4)
White blood cells (×109/L)12.8(0.42-51.55)
Platelet (×109/L)196(9-445)
Hemoglobin (g/dL)11.4(4.3-17.3)
Hematocrit (%)33.8(12.5-49.2)
Prothrombin time in INR, ratio1.18(0.93-3.62)
Total bilirubin (mg/dL)0.8(0.3-3.8)
AST (U/dL)27(8-1470)
ALT (U/dL)19(5-2100)
Lactate dehydrogenase (IU/dL)521(138-2492)
BUN (mg/dL)24.05(8.2-184.1)
Creatinine (mg/dL)1.06(0.3-23.8)
Final diagnosis
Urinary tract infection (, %)32(40%)
Respiratory tract infection (, %)36(45%)
Digestive tract infection (, %)4(5%)
Hepatobiliary tract infection (, %)3(3.7%)
Others (, %)5(6.3%)
Underlying disease
HTN/DM (, %)10/6(12.5/7.5%)
HTN + DM (, %)13(16.3%)
Prognosis
Survivor (, %)63(78.7%)
Nonsurvivor (, %)17(21.2%)

aData are presented as median (range) for continuous variables and frequency (%) for categorical variables. APACHE: acute physiology and chronic health evaluation; SOFA: sequential organ failure assessment; AST: aspartate aminotransferase; ALT: alanine aminotransferase; HTN: hypertension; DM: diabetes mellitus.