Diagnosis and Prognosis of Sepsis Based on Use of Cytokines, Chemokines, and Growth Factors
Table 1
Clinical characteristics and baseline demographics of the 80 sepsis patientsa.
Characteristics
Demographics
Female/male (, %)
36/44
(45/55%)
Age (years, range)
74.5
(38-87)
Age >65/<65
58/22
(72.5/27.5%)
Clinical parameters
APACHE II score
26.2
(3-38.9)
SOFA score
4
(2-13)
Laboratory data
PaO2/FiO2
140
(45-920)
Lactate (mmol/L)
2.1
(0.3-14.4)
White blood cells (×109/L)
12.8
(0.42-51.55)
Platelet (×109/L)
196
(9-445)
Hemoglobin (g/dL)
11.4
(4.3-17.3)
Hematocrit (%)
33.8
(12.5-49.2)
Prothrombin time in INR, ratio
1.18
(0.93-3.62)
Total bilirubin (mg/dL)
0.8
(0.3-3.8)
AST (U/dL)
27
(8-1470)
ALT (U/dL)
19
(5-2100)
Lactate dehydrogenase (IU/dL)
521
(138-2492)
BUN (mg/dL)
24.05
(8.2-184.1)
Creatinine (mg/dL)
1.06
(0.3-23.8)
Final diagnosis
Urinary tract infection (, %)
32
(40%)
Respiratory tract infection (, %)
36
(45%)
Digestive tract infection (, %)
4
(5%)
Hepatobiliary tract infection (, %)
3
(3.7%)
Others (, %)
5
(6.3%)
Underlying disease
HTN/DM (, %)
10/6
(12.5/7.5%)
HTN + DM (, %)
13
(16.3%)
Prognosis
Survivor (, %)
63
(78.7%)
Nonsurvivor (, %)
17
(21.2%)
aData are presented as median (range) for continuous variables and frequency (%) for categorical variables. APACHE: acute physiology and chronic health evaluation; SOFA: sequential organ failure assessment; AST: aspartate aminotransferase; ALT: alanine aminotransferase; HTN: hypertension; DM: diabetes mellitus.