Diagnosis and Prognosis of Sepsis Based on Use of Cytokines, Chemokines, and Growth Factors

Table 5

Univariate and multivariate analysis for the prediction of prognosis among sepsis patients.

	Univariate				Multivariate
	Odds ratio	95% CI		value	Odds ratio	95% CI		value
Age	1.058	0.999	1.121	0.038	1.092	1.012	1.177	0.022
AST				NS
ALT				NS
CRP				NS
PCT				NS
Creatinine				NS
Total bilirubin				NS
APACHE II score				NS
SOFA score	1.279	1.064	1.539	0.009	1.349	1.074	1.695	0.010
IL-10	1.001	1.000	1.002	0.034
IL-17A	1.019	1.001	1.037	0.036
IL-18	1.010	1.000	1.019	0.047
CXCL10	1.002	1.000	1.004	0.014
EGF	0.973	0.957	0.989	0.001	0.979	0.959	1.001	0.050
NGF	0.984	0.974	0.995	0.005
SCF	0.975	0.958	0.993	0.007
VEGF-D	0.998	0.975	1.000	0.050

AST: aspartate aminotransferase; ALT: alanine aminotransferase; CRP: C-reactive protein; PCT: procalcitonin; APACHE: acute physiology and chronic health evaluation; SOFA: sequential organ failure assessment; IL: interleukin; CXCL: chemokine (C-X-C motif) ligand; EGF: epidermal growth factor; NGF: nerve growth factor; SCF: stem cell factor; VEGF-D: vascular endothelial growth factor D precursor.