Disease Markers / 2019 / Article / Tab 2

Research Article

Evaluation of Matrix Metalloproteinase 9 Serum Concentration as a Biomarker in Malignant Mesothelioma

Table 2

Association of MMP9 serum levels with treatment response.

Serum MMP9CR+PR
Median (25-75%) (ng/ml)
SD+PD
Median (25-75%) (ng/ml)
OR (95% CI)OR (95% CI) adj adj

Before treatment757.4 (546.1-1175.5)683.5 (483.4-1242.3)1.014 (0.938-1.095)0.7281.032 (0.951-1.118)0.452
After treatment449.3 (226.4-763.3)440.5 (269.2-640.3)1.036 (0.925-1.160)0.5421.092 (0.983-1.236)0.164
Change after treatment-299.4 (-603.1 to -8.5)-286.3 (-648.5 to -74.2)1.012 (0.925-1.107)0.7971.020 (0.925-1.124)0.696

Odds ratios (ORs) calculated for an increase of MMP9 levels for 100 ng/ml. Adj: adjusted for C-reactive protein; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.