The Prognostic Significance of Protein Expression of CASZ1 in Clear Cell Renal Cell Carcinoma

Table 3

Multivariate analysis of overall, cancer-specific, and progression-free survival.

	OS		CSS		PFS
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
CASZ1
Low vs. high	0.589 (0.437-0.794)	0.001	0.526 (0.367-0.754)	<0.001	0.558 (0.417-0.747)	<0.001
WHO/ISUP grade
1, 2 vs. 3, 4	1.775 (1.317-2.391)	<0.001	3.387 (2.129-5.389)	<0.001	1.866 (1.386-2.513)	<0.001
T category
T1, T2 vs. T3, T4	1.855 (1.378-2.498)	<0.001	2.538 (1.768-3.645)	<0.001	2.431 (1.813-3.259)	<0.001
N category
N0/Nx vs. N1	5.417 (3.037-9.662)	<0.001	6.190 (3.346-11.451)	<0.001	3.918 (2.157-7.116)	<0.001
M category
M0 vs. M1	6.497 (4.636-9.105)	<0.001	9.385 (6.429-13.702)	<0.001	7.677 (5.469-10.778)	<0.001

OS: overall survival; CSS: cancer-specific survival; PFS: progression-free survival; HR: hazard ratio; CI: confidence interval.