Research Article

ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population

Table 4

Distribution of ABCB1 genotypes frequencies in drug-responsive and drug-resistant patients.

SNPABCB1 genotypeDrug-resistant patients ()Drug-responsive patients
()
ORs95% CI value2
%%

ABCB1 C1236TCC vs. CT+TT61217340.2650.094-0.7450 .0126.830
CT vs. CC+TT185627540.4790.215-1.0680.0723.270
TT vs. CC+CT26526127.9442.872-21.978≤0.00118.380
TT vs. CC265261212.2783.393-44.433≤0.00116.740
CT vs. CC185627541.8890.625-5.7050.2602.890
TT vs. CT26526126.5002.231-18.940≤0.00112.990

ABCB1 G2677TGG vs. GT+TT1020363.9171.008-15.2200.0494.330
GT vs. GG+TT132641820.0770.030-0.201≤0.00131.560
TT vs. GG+GT27546128.6093.110-23.832≤0.00119.950
TT vs. GG27546121.3500.282-6.4530.7070.140
GT vs. GG132641820.0950.023-0.3990.00112.980
TT vs. GT275461214.1924.808-41.8950.00127.500

ABCB1 C3435TCC vs. CT+TT112224480.3060.128-0.7290.0087.430
CT vs. CC+TT91820400.3290.132-0.8240.0185.880
TT vs. CC+CT3060612113.952-30.614≤0.00125
TT vs. CC306061210.9093.523-33.782≤0.00119.590
CT vs. CC91820400.9820.339-2.8400.9730
TT vs. CT306061211.1113.422-36.081≤0.00118.300

Values ( and %). ORs: odds ratio; 95% CI: confidence interval; significant value ≤ 0.05; 2: chi-square.