Research Article
Alanine Aminotransferase and Body Composition in Obese Men and Women
Table 1
Clinical characteristics of the subjects. Numbers (%) or mean (SD) is presented.
| | Variables | Total group () | Men () | Women () | |
| | Age (years) | 47.5 (11.4) | 47.8 (10.8) | 47.4 (11.8) | 0.15 | | Use of antihypertensive drugs | 93 (20.8) | 33 (21.0) | 60 (20.6) | 1.0 | | Statin use | 43 (9.6) | 12 (7.6) | 31 (10.7) | 1.0 | | NSAID | 74 (16.5) | 27 (17.2) | 47 (16.2) | 1.0 | | H2-blocking drugs | 14 (3.1) | 3 (1.9) | 11 (3.8) | 1.0 | | Antidepressants | 25 (5.6) | 10 (6.4) | 15 (5.2) | 0.52 | | Height (cm) | 169.3 (8.9) | 178.3 (6.1) | 164.5 (6.0) | 0.76 | | Weight (kg) | 99.3 (14.2) | 109.2 (11.2) | 94.0 (11.7) | 0.020 | | BMI (kg/m2) | 34.6 (3.9) | 34.3 (3.6) | 34.7 (4.1) | 0.15 | | Obesity () | 406 (90.6) | 141 (89.8) | 265 (91.1) | 0.73 | | Overweight () | 42 (9.4) | 16 (10.2) | 26 (8.9) | 1.0 | | Fat mass (kg) | 40.6 (8.3) | 36.7 (8.4) | 42.6 (7.6) | 0.018 | | Lean mass (kg) | 54.2 (11.7) | 67.5 (7.4) | 47.1 (5.9) | 0.027 | | Fat mass index (kg/m2) | 14.3 (3.4) | 11.5 (2.6) | 15.8 (2.8) | <0.0001 | | Lean mass index (kg/m2) | 18.7 (2.6) | 21.2 (1.9) | 17.4 (1.9) | <0.0001 | | ALT (U/L) | 31.2 (17.5) | 38.5 (15.9) | 27.3 (17.1) | <0.0001 | | High ALT | 38 (8.5) | 4 (2.5) | 34 (11.7) | 0.001 | | AST (U/L) | 25.7 (10.0) | 29.0 (8.7) | 24.0 (10.3) | 0.72 | | High AST | 37 (8.3) | 12 (7.6) | 25 (8.6) | 0.86 | | GGT (U/L) | 32.0 (38.8) | 37.2 (39.2) | 27.4 (37.9) | <0.0001 | | Creatine kinase (U/L) | 121.6 (120.3) | 178.5 (180.7) | 91.0 (46.3) | <0.0001 | | S-glucose (mmol/L) | 5.35 (0.64) | 5.47 (0.59) | 5.27 (0.64) | 0.92 | | S-HbA1c (%) | 5.66 (0.38) | 5.67 (0.42) | 5.65 (0.36) | 0.14 | | Hs-CRP (mg/dL) | 4.08 (4.87) | 3.30 (4.71) | 4.45 (4.82) | 0.08 | | S-total cholesterol (mmol/L) | 5.37 (1.00) | 5.40 (0.89) | 5.36 (1.06) | 0.022 | | Physical activity score (MET-min/week) | 3207.0 (3836.0) | 3046.7 (4273.2) | 3297.8 (3587.4) | <0.0001 |
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BMI: body mass index; ALT: alanine transaminase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; Hs-CRP: high sensitive C-reactive protein; MET: metabolic equivalent; NSAID: nonsteroid antiflogistic drugs. Analyzed log-transformed. Above reference limit. |
