Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid Arthritis

Table 4

Binary logistic regression for 4 circRNAs in discriminating new-onset RA patients from HC.

Variables	AUC	value	95% C.I.	Sensitivity	Specificity
Hsa_circ_0001947+hsa_circ_0002715	0.723	<0.0001	0.618-0.827	55.93	82.86
Hsa_circ_0001947+hsa_circ_0000367	0.727	<0.0001	0.626-0.829	67.8	71.43
Hsa_circ_0001947+hsa_circ_0035197	0.743	<0.0001	0.639-0.847	74.6	65.71
Hsa_circ_0002715+hsa_circ_0000367	0.715	0.0010	0.611-0.819	64.41	74.29
Hsa_circ_0002715+hsa_circ_0035197	0.758	<0.0001	0.656-0.861	72.88	71.43
Hsa_circ_0000367+hsa_circ_0035197	0.745	<0.0001	0.644-0.845	89.83	45.71
Hsa_circ_0001947+hsa_circ_0002715+hsa_circ_0000367	0.727	<0.0001	0.626-0.828	69.49	68.57
Hsa_circ_0001947+hsa_circ_0002715+hsa_circ_0035197	0.754	<0.0001	0.651-0.856	67.8	74.29
Hsa_circ_0002715+hsa_circ_0000367+hsa_circ_0035197	0.754	<0.0001	0.655-0.852	77.97	60
Hsa_circ_0001947+hsa_circ_0000367+hsa_circ_0035197	0.744	<0.0001	0.644-0.845	76.27	60
Hsa_circ_0001947+hsa_circ_0002715+hsa_circ_0000367+hsa_circ_0035197	0.753	<0.0001	0.654-0.851	79.66	60

Area under the curve (AUC); circular RNAs (circRNAs); healthy controls (HC); rheumatoid arthritis (RA).