Disease Markers / 2019 / Article / Tab 1

Research Article

Prognostic Value of MicroRNAs in Patients after Myocardial Infarction: A Substudy of PRAGUE-18

Table 1

Baseline characteristics.

All patientsSurvivorsNonsurvivors values

Median (5th-95th percentile)
Number of patients1221166
Age (years)61.1 (40.4–76.8)61.1 (40.1–76.7)65.7 (56.1–81.0)0.166
Men (number, %)96 (78.7%)91 (78.4%)5 (83.3%)0.999
BMI27.6 (22.2–34.3)27.6 (22.1–34.3)26.7 (24.7–44.1)0.929
Drug used: prasugrel (number, %)65 (53.3%)62 (53.4%)3 (50.0%)0.999
Drug used: ticagrelor (number, %)57 (46.7%)54 (46.6%)3 (50.0%)
STEMI (number, %)121 (99.2%)115 (99.1%)6 (100.0%)0.999
Left bundle branch block (LBBB) (number, %)1 (0.8%)1 (0.9%)0 (0.0%)0.999
Right bundle branch block (RBBB) (number, %)1 (0.8%)1 (0.9%)0 (0.0%)0.999
Hyperlipidaemia (number, %)36 (29.5%)35 (30.2%)1 (16.7%)0.669
Obesity (number, %)23 (18.9%)22 (19.0%)1 (16.7%)0.999
Arterial hypertension (number, %)56 (45.9%)52 (44.8%)4 (66.7%)0.412
Smoking (number, %)84 (68.9%)80 (69.0%)4 (66.7%)0.999
Diabetes mellitus (number, %)17 (13.9%)16 (13.8%)1 (16.7%)0.999
Time since the first symptoms to admission (hours)3.0 (0.5–36.0)3.0 (0.5–12.0)6.0 (3.0–72.0)0.061
Left ventricular ejection fraction (%)50.0 (30.0–60.0)55.0 (30.0–60.0)45.0 (30.0–50.0)0.054
Laboratory values (median (5th-95th percentile))
hsTnT (at admission) (ng/L)86.0 (12.0–1325.0)84.0 (12.0–1325.0)201.5 (27.0–4978.0)0.257
hsTnT (24 hours after admission) (ng/L)2432.0 (377.0–9651.0)2324.0 (368.0–9651.0)4306.5 (1526.0–15114.0)0.201
Myoglobin (at admission) (μg/L)198.0 (30.0–1385.0)176.0 (30.0–1547.0)652.0 (161.0–1317.0)0.066
Creatine kinase (at admission) (μkat/L)3.9 (1.4–23.7)3.8 (1.3–23.7)6.4 (2.6–26.8)0.097
NT-proBNP (at admission) (ng/L)757.0 (105.0–4142.0)666.5 (104.0–4285.0)1373.5 (904.0–3096.0)0.074
Cystatin C (at admission) (mg/L)121; 0.99 (0.80–1.47)1.00 (0.79–1.49)0.92 (0.85–1.09)0.417
GDF-15 (at admission) (ng/L)807.1 (372.8–1827.7)796.3 (372.8–1827.7)1044.9 (357.3–1848.8)0.305

GDF-15 = growth/differentiation factor 15; hsTnT = high-sensitivity troponin T; NT-proBNP = N-terminal prohormone of brain natriuretic peptide; STEMI = acute myocardial infarction with ST-segment elevation.

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