Disease Markers / 2019 / Article / Tab 1

Research Article

Investigation of Key Genes and Pathways in Inhibition of Oxycodone on Vincristine-Induced Microglia Activation by Using Bioinformatics Analysis

Table 1

31 candidate prioritization differentially expressed genes from the ToppGene.

RankGene nameGene symbolInteractant countScoreExpression

1Hemoglobin subunit betaHBB639.22-020.9249
2Platelet factor 4PF4119.08-022.1651
3Hemoglobin subunit alpha 2HBA2537.10-020.5341
4Cystatin E/MCST6386.20-02-0.6299
5Squamous cell carcinoma antigen recognized by T cell 1SART11195.18-02-0.9107
6Insulin-like growth factor 2IGF2243.87-020.6439
7Nephroblastoma overexpressedNOV183.71-020.8820
8Kruppel-like factor 5KLF5543.58-020.5621
9Interferon regulatory factor 7IRF7483.26-02-0.5762
10Mitochondrial ribosomal protein L11MRPL11653.22-02-0.8362
11Phospholipase A2 group IIAPLA2G2A292.89-021.3113
12Solute carrier family 47 member 1SLC47A1272.83-020.7889
13Myxovirus (influenza virus) resistanceMX1432.75-02-0.7250
14SCY1-like pseudokinase 1SCYL1322.19-02-1.0549
15C-X-C motif chemokine ligand 10CXCL10101.82-020.9672
16C-X-C motif chemokine ligand 9CXCL991.42-020.8880
17Tektin 2TEKT2191.34-020.5100
18Secreted frizzled-related protein 2SFRP2201.25-020.7842
19Sterol-C5-desaturaseSC5D121.14-02-0.5514
20HemogenHEMGN171.07-020.564234
21Ring finger protein 113A2RNF113A209.74-03-1.7287
22Guanine nucleotide binding protein (G protein), gamma 11GNG11119.36-030.7967
23Troponin T2, cardiac typeTNNT2117.86-030.5085
24Corticotropin-releasing hormoneCRH55.88-03-0.8934
25Gap junction protein, beta 6GJB664.49-030.5675
26Alpha hemoglobin-stabilizing proteinAHSP73.88-031.1388
27FibromodulinFMOD73.14-030.5468
28Arachidonate 15-lipoxygenaseALOX1542.46-033.8408
29Peroxisomal membrane protein 4PXMP419.57-04-1.2075
30Cartilage intermediate layer proteinCILP27.60-040.6077
31Rh blood group, D antigenRHD12.97-040.5245