Altered Serum MicroRNA Profile May Serve as an Auxiliary Tool for Discriminating Aggressive Thyroid Carcinoma from Nonaggressive Thyroid Cancer and Benign Thyroid Nodules

Table 3

Differentially expressed miRNAs among the MTC, benign nodule, and the healthy control groups by qRT-PCR^a.

miRNA	MTC ()	Benign nodule ()	Healthy control ()	value^b	value^c	value^d
miR-222-3p				<0.001	<0.001	0.098
miR-17-5p				<0.01	<0.001	0.113
miR-451a				0.533	<0.05	<0.01

MTC: medullary thyroid carcinoma. ^aThe relative contents of miRNAs are normalized to let-7d/g/i and presented as . ^bDifference between the MTC group and the benign nodule group. ^cDifference between the MTC group and the healthy control group. ^dDifference between the benign nodule group and the healthy control group.