Research Article

Prevalence of Syndecan-1 (CD138) Expression in Different Kinds of Human Tumors and Normal Tissues

Table 2

CD138 expression in normal human tissues.

Organ systemsCell type (strong staining +++)Cell type (moderate staining ++)Cell type (weak staining +)

Urogenital kidney, urinary bladder, prostate, seminal vesicle, epididymisTubular cells, collecting duct cellsUrothelial basal/intermediate/umbrella cells, basal cells of the prostate and seminal vesicle, some columnar cells of the epididymis

Gynecology breast, cervix uteri, uterus corpus, placenta (early and mature)Ectocervical: basal cellsEctocervical: intermediate cells, superficial endometrial cells, cytotrophoblasts, syncytiotrophoblastsBreast: excretory duct cells and myoepithelial cells, endocervical: some mucous cells; endometrium: some basalis type cells and some secretory cells, decidual cells

Skin, sebaceous glandBasal cells, keratocytes, peripheral germinative cells of the sebaceous glandSebaceous gland cells

Lip, oral cavity, tonsilKeratocytes, squamous epithelial cells

Salivary glands parotid gland, submandibular gland, sublingual glandSerous cellsSome serous cells, some columnar ductal cells, myoepithelial cells, intralobular duct cells of the submandibular gland, columnar ductal cells of the sublingual gland

Gastrointestinal tract esophagus, stomach, duodenum, ileum, colon descendens, rectum, anal canal and transitional mucosa, appendix vermiformisSquamous basal cells of the esophagus, keratinocytes, parietal cells and chief cells of the stomach, crypt cells, goblet cells, absorptive cells, basal cells and keratinocytes of the anal skinMucous secreting cells and columnar cells of the stomach, Brunner glands

GallbladderColumnar cells, mucous gland cells

LiverHepatocytesInterlobular bile duct cells

PancreasExcretory duct cells

Airway lung, bronchus, sinus paranasalBasal cells, ciliated cells, goblet cellsPneumocytes, bronchus glands: basal cells and serous cells, goblet cells of the sinus paranasales

Endocrine adrenal gland, parathyroidCortical cellsOxyphil cells and chief cells of the parathyroid