Diagnosis of Urinary Tract Infections by Urine Flow Cytometry: Adjusted Cut-Off Values in Different Clinical Presentations
Table 2
Discriminatory accuracy of UFC leucocyte and UFC bacterium counts measured by the area under the receiver operating curve of the logistic regression to predict significant bacterial growth in urine culture.
Total () SBU (%)
AUC (95% CI)
Training set () SBU (%)
Validation set () SBU (%)
Sex
Male
32.3
0.95 (0.92, 0.97)
29.9
34.6
Female
49.2
0.88 (0.85, 0.92)
48.7
49.7
Age
>65 years
46.3
0.95 (0.92, 0.97)
45.4
47.2
≤65 years
35.8
0.90 (0.86, 0.93)
34.5
37.2
Dysuria
Yes
54.5
0.88 (0.82, 0.94)
57.1
51.8
No
37.3
0.92 (0.90, 0.95)
35.1
39.6
Urinary frequency
Yes
61.5
0.88 (0.80, 0.96)
70.0
52.6
No
37.4
0.92 (0.90, 0.94)
34.5
40.3
Fever (>38.0°C)1
Yes
32.8
0.94 (0.90, 0.98)
28.1
37.5
No
43.9
0.91 (0.88, 0.94)
44.3
43.5
UTI-specific abdominal pain2
Yes
54.6
0.88 (0.81, 0.93)
54.1
55.2
No
37.0
0.92 (0.90, 0.95)
35.5
38.7
Diabetes
Yes
44.1
0.94 (0.90, 0.98)
41.9
46.0
No
39.4
0.91 (0.89, 0.94)
38.4
40.5
Renal insufficiency
Yes
39.9
0.93 (0.89, 0.96)
37.5
42.7
No
40.7
0.92 (0.89, 0.94)
40.0
41.4
Immunosuppression
Yes
33.5
0.92 (0.88, 0.96)
33.3
33.6
No
44.2
0.91 (0.89, 0.94)
42.1
46.4
Total
40.2
—
39.1
41.8
1Two values (one of training and one of the validation set) were missing; thus, .2This includes lower abdominal, suprapubic, and flank pain. Abbreviations: AUC: area under the receiver operating curve; CI: confidence interval; SBU: significant bacterial growth in urine culture; UFC: urine flow cytometry; UTI: urinary tract infection.
