High Serum Uric Acid Is Associated with Tubular Damage and Kidney Inflammation in Patients with Type 2 Diabetes
Table 2
Biochemical parameters of the study participants () stratified according to tertiles of serum uric acid concentration.
1st tertile
2nd tertile
3rd tertile
value
Urinary KIM-1 (pg/mL)
96 (56–144)
77 (58–95)
97 (79–159)
0.039
Urinary KIM-1 (ng/g creat)
121 (76–265)
76 (48–107)
125 (88–200)
0.009
Urinary IL-1 (pg/mL)
93 (73–131)
82 (66–100)
100 (78–143)
0.065
Urinary IL-1 (ng/g creat)
108 (67–192)
88 (53–156)
123 (94–187)
0.057
Urinary IL-6 (pg/mL)
115 (91–144)
99 (92–124)
121 (96–155)
0.098
Urinary IL-6 (ng/g creat)
129 (88–227)
124 (70–184)
171 (103–213)
0.141
Urinary IL-10 (pg/mL)
62 (46–90)
69 (51–135)
64 (39–130)
0.379
Urinary IL-10 (ng/g creat)
76 (47–152)
93 (54–164)
87 (40–178)
0.846
Urinary TNF-alpha (pg/mL)
137 (110–161)
128 (110–139)
132 (106–187)
0.267
Urinary TNF-alpha (ng/g creat)
142 (104–267)
149 (83–189)
176 (124–251)
0.272
Data are expressed as median and interquartile ranges. Parameters are reported as absolute values and as values normalized by urinary creatinine concentration.
