Maternal Serum Angiogenic Factor sFlt-1 to PlGF Ratio in Preeclampsia: A Useful Marker for Differential Diagnosis and Prognosis Evaluation in Chinese Women
sFlt-1/PlGF ratio in PE, GH, chrHTN, CTD, proteinuria, and controls. Box-whisker plots displayed the sFlt-1/PlGF ratio in patients with PE, GH, chrHTN, pregnancies with CTD or proteinuria, and controls. Boxes indicate interquartile range; whisker indicates range; error bars indicate median. ○ means mild outliers. means extreme outliers. The cutoff of 97.2 was drawn into the graph as a solid line. (a) The logarithmic distribution of the sFlt-1/PlGF ratio in patients with PE/GH/chrHTN/controls. The average Flt-1/PlGF ratio was significantly higher in PE <34 weeks () than in GH (), chrHTN (), or controls () <34 weeks (all ). PE ≥34 weeks () was compared with chrHTN () and controls () ≥34 weeks (all ), though the difference did not reach statistical significance between PE and GH ≥34 weeks () (). (b) The logarithmic distribution of the sFlt-1/PlGF ratio in patients with PE, GH, chrHTN, pregnancies with CTD or proteinuria, and controls. The sFlt-1/PlGF ratio was higher in PE than in GH, chrHTN, CTD (), proteinuria (), and controls (all ), while no significant differences between any other two groups.