Association of Common Variants in HNF1A Gene with Serum AFP Level in Healthy Chinese Individuals and HCC Patients

Table 2

Association of rs2464196 and rs1169310 genotypes with AFP levels in healthy Chinese subjects.

	rs2464196					rs1169310
		β	95% CI	SE			β	95% CI	SE
Model 1	0.017	-0.078	-0.114, -0.043	0.018	0.000018	0.013	-0.070	-0.106, -0.034	0.018	0.000139
Model 2	0.028	-0.080	-0.115, -0.044	0.018	0.000012	0.024	-0.072	-0.108, -0.036	0.018	0.000087
Model 3	0.066	-0.072	-0.108, -0.037	0.018	0.000056	0.063	-0.065	-0.100, -0.029	0.018	0.000339

Model 1: no adjustment; model 2: adjusted for age, gender, and BMI; model 3: adjusted for age, gender, BMI, blood pressure, LDL, HDL, TC, lnAST, lnALT, lnTG, lnGGT, lnCRP, FPG, and fatty liver. β represents the unstandardized beta coefficients (β) for the effects of HNF1A polymorphisms on the AFP levels. values for the associations of the rs2464196 or rs1169310 genotypes with the AFP level. values that passed Bonferroni correction ().