Disease Markers / 2019 / Article / Tab 1

Research Article

miR-34b/c rs4938723 T>C Decreases Neuroblastoma Risk: A Replication Study in the Hunan Children

Table 1

miR34b/c rs4938723 T>C polymorphism and neuroblastoma susceptibility.

GenotypeCases ()Controls ()aCrude OR (95% CI)Adjusted OR (95% CI)bb

rs4938723 T>C ()
TT100 (61.73)117 (43.33)1.001.00
TC47 (29.01)123 (45.56)0.45 (0.29-0.69)0.00020.46 (0.30-0.71)0.0004
CC15 (9.26)30 (11.11)0.59 (0.30-1.15)0.1190.62 (0.32-1.23)0.175
Additive0.00080.62 (0.46-0.85)0.00260.64 (0.47-0.88)0.005
Dominant62 (38.27)153 (56.67)0.00020.47 (0.32-0.71)0.00020.49 (0.33-0.73)0.0005
Recessive147 (90.74)240 (88.89)0.5420.82 (0.43-1.57)0.5420.86 (0.45-1.67)0.665

OR: odds ratio; CI: confidence interval.a test for genotype distributions between neuroblastoma cases and cancer-free controls.bAdjusted for age and gender.

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