Identification of Key Pathways and Genes in the Orai2 Mediated Classical and Mesenchymal Subtype of Glioblastoma by Bioinformatic Analyses

Figure 4

Orai2-related biological process. Orai2-related biological process by (a) gene ontology analysis in TCGA datasets. (b) Association between Orai2 and the main proteins of the JNK pathway in TCGA. Red ribbons indicate positive correlation of two terms while green ribbons indicate negative correlation. The width of ribbon and scale of colors indicate correlation coefficient. Association in Orai2 expression and GSC self-renewal, apoptosis, and EMT-related molecules in (d) classical and (e) mesenchymal TCGA datasets. (c) The PPI network also confirmed these findings.

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