Review Article

Preoperative Anemia or Low Hemoglobin Predicts Poor Prognosis in Gastric Cancer Patients: A Meta-Analysis

Table 1

The baseline characteristics and design variables of included studies on preoperative anemia and gastric cancer prognosis.

ArticleCountryYearStudy typeNumber of patients (M/F)aAge: (range)bRate of anemia (/)cFollow-up: (range)dOutcome measuredStudy quality

LiuChina2018Cohort2163 (1442/721)Median: 58 (14-89)314/1035Median: 28 (3-185)OS7
WangChina2018Cohort859 (672/187)Median: 64 (IQR: 16)434/859Median: 60.9DFS, OS6
ChenChina2017Cohort292 (205/87)Mean: 57 (range: 28-77)144/292NRDFS, OS6
XueChina2017Cohort269 (202/67)Mean: 65.77 (95% CI: 64.42-67.12)84/269Median: 40 (1-108)OS8
WuChina2017Cohort210 (128/82)Median: 60 (36-79)53/21060DFS8
LeeKorea2017Cohort309 (77/232)Median: 60 (29-82)NRMedian: 33.8 (2.6-67.5)DFS, OS6
HuChina2017Cohort3012 (2239/773)Range: 51-68NRMedian: 44.05 (1.1-183.3)OS6
QianChina2016Cohort579 (405/174)Median: 58 (18-85)252/579Median: 44 (12-81)OS7
CuiChina2016Cohort1150 (817/333)Range: 23-93NRMedian: 40OS6
EoKorea2015Cohort299 (195/104)Median: 59 (25-92)NRMedian: 37.2 (1.7-91.4)DFS, OS8
ZhouChina2014Cohort605 (405/200)Mean: 90/605Median: 35.4 (1-78)OS7
RauseiItaly2013Cohort224 (147/77)Mean: 111/224Median: 48OS5
MohriJapan2010Cohort357 (245/112)Mean: 63.4 (range: 32-87)NRMedian: 68 (1-70)OS6
GorbunovCzech Republic2005Cohort283 (182/101)NR179/283Mean: 73.2 (range: 12-132)OS6
ShenKorea2005Cohort1688 (1162/526)Mean: (range: 22-85)673/1688Median: 85 (range: 0-138)DFS, OS8
WuTaiwan1997Cohort510 (420/90)NR84/510NROS6
JatzkoAustria1995Cohort345 (221/124)Mean: 67 ± 0.5745/339Mean: 65.5OS7

aM/F presents the number of males and females, respectively. bThe age of patients was summarized as mean with standard deviation or median with range. cThe rate of patients with preoperative anemia. dThe follow-up period was summarized as mean with standard deviation or median with range. Abbreviations: DFS: disease-free survival; IQR: interquartile range; M/F: males/females; NR: not reported; OS: overall survival; SD: standard deviation.