Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

Figure 4

Association between adipose tissue IL-33 and CD68 and CD302 in individuals with varying degrees of glycemia. (a) IL-33 was inversely correlated (although statistically nonsignificant) with CD68 in individuals with normoglycemia (), prediabetes (), and T2D (). (b) Higher levels of IL-33 were associated with significantly lower CD68 in individuals with T2D but not in those with normoglycemia or prediabetes. (c) IL-33 was directly correlated with CD302 in individuals with normoglycemia () and T2D () but not in those with prediabetes (). (d) Higher levels of IL-33 were associated with higher CD302 in individuals with normoglycemia (although statistically nonsignificant) and T2D (statistically significant) but not in those with prediabetes. IL-33: interleukin-33; CD68: cluster of differentiation 68; CD302: cluster of differentiation 302; NL: normoglycemia; T2D: type 2 diabetes; Meds: glucose-lowering medications.

(a)

(b)

(c)

(d)